"A simulation study of the impact of drug-IKr binding mechanisms on ..."

Julio Gomis-Tena, Fernando Escobar, Lucía Romero (2025)

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DOI: 10.1016/J.CMPB.2024.108566

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type: Journal Article

metadata version: 2025-01-25

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Julio Gomis-Tena, Fernando Escobar, Lucía Romero:
A simulation study of the impact of drug-IKr binding mechanisms on biomarkers of proarrhythmic risk reveals a crucial role in reverse use-dependence of action potential duration and a marked influence on the vulnerable window. Comput. Methods Programs Biomed. 260: 108566 (2025)

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