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ORCIDLucía Romero 0001
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- affiliation: Technical University of Valencia, Centro de Investigación e Innovación en Bioingeniería, CI2B, Spain
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2020 – today
- 2025
[j10]Julio Gomis-Tena
, Fernando Escobar, Lucía Romero:
A simulation study of the impact of drug-IKr binding mechanisms on biomarkers of proarrhythmic risk reveals a crucial role in reverse use-dependence of action potential duration and a marked influence on the vulnerable window. Comput. Methods Programs Biomed. 260: 108566 (2025)- 2024
- [j9]Fernando Escobar, Soren Friis, Nouran Adly, Nina Brinkwirth, Julio Gomis-Tena, Javier Saiz, Dan A. Klaerke, Sonja Stoelzle-Feix, Lucía Romero:
Experimentally validated modeling of dynamic drug-hERG channel interactions reproducing the binding mechanisms and its importance in action potential duration. Comput. Methods Programs Biomed. 254: 108293 (2024) - [j8]Rebecca Belletti, Joaquín Osca, Lucía Romero Pérez, Javier Saiz:
Influence of genetic mutations to atria vulnerability to atrial fibrillation: An in-silico 3D human atria study. Comput. Methods Programs Biomed. 254: 108307 (2024) - 2023
- [j7]Jordi Llopis-Lorente, Samuel Baroudi, Kévin Koloskoff, Maria Teresa Mora, Matthieu Basset, Lucía Romero, Sylvain Benito, Frédéric Dayan, Javier Saiz, Beatriz Trénor:
Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity. Comput. Methods Programs Biomed. 242: 107860 (2023) - [c8]Violeta Puche-García, Lucía Romero, Javier Saiz:
Computational Study of Drug Effects on Different Atrial Fibrillation Stages. CinC 2023: 1-4 - 2022
- [j6]Fernando Escobar, Julio Gomis-Tena, Javier Saiz, Lucía Romero:
Automatic modeling of dynamic drug-hERG channel interactions using three voltage protocols and machine learning techniques: A simulation study. Comput. Methods Programs Biomed. 226: 107148 (2022) - [c7]Rebecca Belletti, Lucía Romero, Javier Saiz:
Computational Study of the Effects of AF-related Genetic Mutations in 3D Human Atrial Model. CinC 2022: 1-4 - 2020
- [j5]Julio Gomis-Tena, Brandon M. Brown, Jordi Cano, Beatriz Trénor, Pei-Chi Yang, Javier Saiz, Colleen E. Clancy, Lucía Romero:
When Does the IC50 Accurately Assess the Blocking Potency of a Drug? J. Chem. Inf. Model. 60(3): 1779-1790 (2020) - [j4]Jordi Llopis-Lorente, Julio Gomis-Tena, Jordi Cano, Lucía Romero, Javier Saiz, Beatriz Trénor:
In Silico Classifiers for the Assessment of Drug Proarrhythmicity. J. Chem. Inf. Model. 60(10): 5172-5187 (2020) - [c6]Rebecca Belletti, Laura Martinez-Mateu, Lucía Romero Pérez, Javier Saiz:
Simulation Study of the Arrhythmogenic Effects of Two Missense Mutations in Human Atrial Fibrillation. CinC 2020: 1-4 - [c5]Fernando Escobar, Julio Gomis-Tena, Javier Saiz, Lucía Romero:
Prediction of IKr Blocker Channel State Preference Based on Voltage Clamp Simulations Using Machine Learning Techniques. CinC 2020: 1-4
2010 – 2019
- 2019
- [j3]Laura Martinez-Mateu, Lucía Romero, Javier Saiz, Omer Berenfeld:
Far-field contributions in multi-electrodes atrial recordings blur distinction between anatomical and functional reentries and may cause imaginary phase singularities - A computational study. Comput. Biol. Medicine 108: 276-287 (2019) - 2018
- [j2]Lucía Romero, Jordi Cano, Julio Gomis-Tena, Beatriz Trénor, Ferran Sanz, Manuel Pastor, Javier Saiz:
In Silico QT and APD Prolongation Assay for Early Screening of Drug-Induced Proarrhythmic Risk. J. Chem. Inf. Model. 58(4): 867-878 (2018) - [j1]Laura Martinez-Mateu, Lucía Romero, Ana Ferrer-Albero, Rafael Sebastián, José F. Rodríguez Matas, José Jalife, Omer Berenfeld, Javier Saiz:
Factors affecting basket catheter detection of real and phantom rotors in the atria: A computational study. PLoS Comput. Biol. 14(3) (2018) - [c4]Jordi Cano, Julio Gomis-Tena, Alexander Amberg, Lennart Anger, Véronique Ballet, Jean-Michel Guillon, Manuel Pastor, Ferran Sanz, Lucía Romero, Javier Saiz:
Development and Validation of an In Silico Rabbit Purkinje Cell Action Potential Model: A Step Towards a Drug Safety Testing Tool. CinC 2018: 1-4 - 2016
- [c3]Laura Martinez-Mateu, Lucía Romero, Ana Ferrer-Albero, José Jalife, Omer Berenfeld, Javier Saiz:
Effect of Multi-Electrode Configurations on Accuracy of Rotor Detection in the Atria. CinC 2016 - 2014
- [c2]Laura Martinez-Mateu, Lucía Romero, Catalina Tobón, Jose Maria Ferrero, José Jalife, Omer Berenfeld, Javier Saiz:
Accurate Characterization of Rotor Activity during Atrial Fibrillation Depends on the Properties of the Multielectrode Grid. CinC 2014: 757-760 - 2013
- [c1]Juan F. Gomez, Karen Cardona, Lucía Romero, Javier Saiz, Beatriz Trénor:
Heterogeneous Electrical Remodeling of the Failing Heart Modulates the Arrythmogenic Substrate. CinC 2013: 49-52
Coauthor Index
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